Effect of Transcatheter Aortic Valve Size and Position on Valve-in-Valve Hemodynamics: An in Vitro Study

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Author(s):

Dr. Ali Azadani

PIs:

Ali N. Azadani, PhD

Michael Reardon, MD

Matheus Simonato

Gabriel Aldea, MD

Georg Nickenig, MD

Ran Kornowski, MD

Danny Dvir, MD

Research Interest:

Transcatheter Aortic Valve Implantation, Aortic Bioprostheses, Valve-in-Valve

Transcatheter heart valve implantation in failed aortic bioprostheses (valve-in-valve [ViV]) is an increasingly used therapeutic option for high-risk patients. However, high postprocedural gradients are a significant limitation of aortic ViV. Our objective was to evaluate Medtronic CoreValve Evolut R ViV hemodynamics in relation to the degree of device oversizing and depth of implantation.

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